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Updated: Jun 4, 2026
Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines
Published on: September 3, 2016
[Comparing two diagnostic methods used for breast neoplasm in a cancer centre in Colima, Mexico]
Freder Sandoval-Hermosillo1, Guillermina A Vázquez-Lara, Leonardo D Farias-Evangelista
1Facultad de Medicina, Universidad de Colima, Colima, México. freder24@hotmail.com
Objective:
Determining the relationship between mammography neoplasm reports and histopathological diagnosis of neoplasms.
Methods:
A descriptive cross-sectional study was carried out. Patients were included who were attending the state cancerology centre (Centro Estatal de Cancerología) in Colima, Mexico. Inclusion parameters were: females having mammography and BIRADS score of 1 or over; females having biopsy and histopathology diagnosis; females of all ages, all clinic stages having a complete clinic record. Frequency, percentages, means and standard deviations were applied for descriptive statistics. Student's t-test, the Chi square test, OR and 95 %CI were applied for inferential statistics. Differences were considered to be significant when p<0.05.
Results:
No relationship between a BIRADS score classified as being benign (BIRADS I-II-III) or malign (BIRADS IV-V) was found with histopathological results (benign or malign) (p=0.0666). Significant relationships by category were found in a separate analysis: category IV (OR=0.024, 95 %CI=0.005-0.11, p=0.0007) and category V (OR=40.5, 95 %CI=9.03-181.3, p=0.0002).
Conclusions:
I, III and V BIRADS scores had a relationship with histopathological diagnosis, while category II and IV BIRADS scores had no relationship. However, only categories 4 and5 were statistically significant.
