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The Protocol for the Early vs. Late Infantile Strabismus Surgery Study
Insights
This study compares early versus late surgery for infantile strabismus. Results will determine the optimal timing for surgical intervention to improve binocular vision and visual acuity in affected children.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Strabismology
Background:
- Infantile strabismus is a common condition affecting young children.
- The optimal timing for surgical intervention remains a subject of debate among specialists.
Purpose of the Study:
- To investigate whether early or late surgical intervention is preferable for infantile strabismus.
- To compare the outcomes of early versus late surgery regarding binocular vision, strabismus angle, and visual acuity.
Main Methods:
- A non-randomized, prospective, multi-centre trial involving infants aged 6 to 18 months.
- Two groups: early surgery (before age 2) and late surgery (between 32 and 60 months).
- Standardized examinations and evaluations at age six.
Main Results:
- Data collection is ongoing.
- Comparison of binocular vision, strabismus angle, and visual acuity between the two surgical timing groups will be performed post-completion.
Conclusions:
- The study aims to provide evidence-based recommendations on the optimal surgical timing for infantile strabismus.
- Findings will contribute to improved management strategies and visual outcomes for children with strabismus.
Abstract:
The Early vs. Late Infantile Strabismus Surgery Study Group is a group of strabismologists and orthoptists who investigate whether early or late surgery is preferable in infantile strabismus, in a non-randomized, prospective, multi-centre trial. Infants between 6 and 18 months of age will receive a standardized entry examination and then be operated either before their second anniversary in clinics A, or between their 32nd and 60th month of age in clinics B. The children will be evaluated at age six. After completion of the study, the two groups can then be compared regarding degree of binocular vision, angle of strabismus and visual acuity of the worse eye relative to the better. Zentrum zur methodischen Betreuung von Therapiestudien, Mrs H. Dinkel, Universität Heidelberg, Im Neuenheimer Feld 305, W-69120 Heidelberg. 49.6221.565500. fax: 564195 Germany PD Dr. H.J. Simonsz, Orthoptics & Neuroophthalmology, Afdeling Oogheelkunde, University Hospital Dijkzigt, Dr. Molewaterplein 40, NL 3015 GD Rotterdam. 3 i. 10.4639222, ask for beeper 3394 fax: 4635105 The Netherlands PD Dr. med. G.H. Rolling, Schule für Orthoptik, Universitäts-Augenklinik, Im Neuenheimer Feld 400, W-69047 Heidelberg. 49.6221.566627/34/39 fax: 565422 Germany Dipl.-Inform. Med. U. Haag, Universität Heidelberg, Zentrum zur methodischen Betreuung von Therapiestudien, Im Neuenheimer Feld 305, W-69120 Heidelberg. 49.6221.564192 fax: 564195 Germany Dr. A. Deák, Augenklinik, Korányi Fasor, U-6720 Szeged. 36.62.12321/10822 fax: 22826 Hungary Mr P. Fells, F.R.C.S., F.C. Ophth., Lower Corridor Suite, Moorfields Eye Hospital, City Road, ECIV 2PD London. 44.71.2533411 fax: 2534696 (lower corridor suite) England Prof. R. Frosini, Istituto di Clinica Oculista dell' Universita di Firenze, Insegnamento di Ottica Fisiopatologica, Viale Morgagni 85,1-50134 Florence. Dr. R. Gomez de Liaño, Nuñez de Balboa 81, E-28006 Madrid. 34.1.5763229/72318 Spain Dr. O. Haugen, Orthoptic Department, Department of Ophthalmology, University of Bergen, N-3021 Bergen. Norway Dr. med. G. Klainguti, Clinique Ophtalmique, 15 Av. de France, CH-1004 Lausanne. 41.21.9637696/250211 Switzerland Prof.Dr. K. Krzystkowa, Ophthal. Clinic Medical Acad., 38 Copernika Str, P-31501 Krakow. 4812.223272/215210/210460/214577/220411 Poland M.C.M.E. van Lammeren, Afdeling Orthoptie, Dienst Oogziekten, U.Z. St. Rafaël, Kapucijnenvoer 33, B-3000 Leuven. Prof. G. Lennerstrand, Institutionen for Oftalmiatrik, Huddinge sjukhus, S-14186 Huddinge. 46.8.7461000/3854/3418 Sweden Dr. med. H. Luka, Abt. f. Schielen, Schwachsichtigkeit und Bewegungsstörungen des Auges, Allgem. öffentl. Krankenhaus der Landeshauptstadt St. Pölten, A-3100 St. Pölten. 43.512.85597/5040 43.2742.62521 (Klappe 2869) Dr. V. Paris, Rue de Luxembourg, 48, B-6900 Marche-en-Famenne. 32.84314749 Belgium Dr. L.J.J.M. Prick-Wenniger, Afdeling Oogheelkunde, A.M.C., Meibergdreef 9, NL 1105 AZ Amsterdam. 31.20.5663881/6715637 The Netherlands Prof. M.A. Quéré, 19, Rue Voltaire, F-44000 Nantes. 33.40.738370/083406 fax: 084649 France Dr. F. Reich-d'Almeida, Rua Castilho, No 65.z:Dto, P-1200 Lissabon. 351.1520619 Dr. med. R. Weidlich, Universitäts-Augenklinik, Leninallee 8, O-4020 Halle. 37.4684.9878/81 Germany.
