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Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
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Ga(III) complexes--the effect of metal coordination on potential systemic absorption after topical exposure

Kirsten Staff1, Marc B Brown, Robert P Chilcott

  • 1Pharmaceutical Science Research Division, King's College London, 150A Stamford Street, Waterloo, London SE19NN, UK.

Toxicology Letters
|February 15, 2011
PubMed

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In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
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