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Updated: Jun 4, 2026

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
Published on: April 11, 2025
Significance of minor traumatic lesions in focal head injuries
Youichi Yanagawa1, Toshihisa Sakamoto
1Department of Traumatology and Critical Care Medicine, National Defense Medical College (NDMC), 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan. yanagawa@ndmc.ac.jp
Abstract:
We investigated the significance of minor traumatic lesions associated with focal head injuries. Patients included in the study were admitted between January 2003 and December 2007 and had sustained a head injury with focal injury and undergone MRI examination including T2(∗)-weighted imaging. Patients were divided into two groups: (i) a T2(∗)-positive group - those who had hypointense lesions at sites other than the original injury site as shown by T2(∗)-weighted MRI (n=12); and (ii) a control group without hypointense lesions at sites other than the original injury (n=25). The median Glasgow Outcome Scale score was significantly lower in the T2(∗)-positive group (median=4; range=4-5) than in the control group (median=5; range=4-5; p=0.003). We conclude that patients with a focal head injury and minor traumatic lesions are likely to have a poorer prognosis than patients without additional minor traumatic lesions.

