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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Related Experiment Video

Updated: Jun 4, 2026

Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma

Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma

Published on: April 3, 2026

Cranial chondrosarcoma and recurrence.

Orin G Bloch¹, Brian J Jian, Isaac Yang

¹Department of Neurological Surgery, University of California at San Francisco, San Francisco, California.

Skull Base : Official Journal of North American Skull Base Society ... [Et Al.]

|February 15, 2011

Summary

This summary is machine-generated.

Recurrence rates for cranial chondrosarcoma are higher with surgery alone or mesenchymal subtypes. This systematic review provides crucial data for managing cranial chondrosarcoma recurrence.

Keywords:

Cranial chondrosarcoma recurrence systematic review

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Area of Science:

Oncology
Neurosurgery
Pathology

Background:

Limited data exist on cranial chondrosarcoma recurrence from single-institution studies.
Accurate recurrence rates are needed for effective patient management.

Purpose of the Study:

To conduct a systematic review of cranial chondrosarcoma recurrence.
To identify predictive factors for tumor recurrence.

Main Methods:

Systematic review of English literature on cranial chondrosarcoma.
Stratification of 560 patients by treatment, history, subtype, and grade.
Analysis of recurrence rates and disease-free intervals.

Main Results:

The 5-year recurrence rate was 22% (median follow-up: 60 months).
Recurrence was more frequent in patients treated with surgery only.
Mesenchymal subtype tumors showed higher recurrence rates.

Conclusions:

This systematic review provides a more accurate actuarial recurrence rate for cranial chondrosarcoma.
Identified predictive factors can guide clinical management strategies.
Further research may focus on optimizing treatment for high-risk subtypes.