Pseudoangiomatous stromal hyperplasia: a case report

Area of Science:

• Breast pathology
• Surgical oncology

Background:

• Pseudoangiomatous stromal hyperplasia (PASH) is a rare benign proliferation of mammary stroma.
• First described in 1986, PASH can present as a breast mass simulating vascular lesions.
• Literature reports of PASH remain infrequent.

Observation:

• A large PASH case is presented in a young female patient.
• The PASH mass mimicked the clinical presentation of inflammatory breast carcinoma.
• Surgical excision was performed for the breast lesion.

Findings:

• Histopathological examination confirmed pseudoangiomatous stromal hyperplasia.
• The lesion's size and presentation mimicked malignancy, posing a diagnostic challenge.
• Complete excision of the PASH was achieved.

Implications:

• This case underscores the importance of considering PASH in the differential diagnosis of breast masses, even those with concerning features.
• Early and accurate diagnosis is crucial for appropriate management and avoiding unnecessary aggressive treatments.
• Successful surgical excision can yield excellent cosmetic outcomes for benign breast conditions like PASH.