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Updated: Jun 4, 2026

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
Published on: June 13, 2014
Adhesion signaling through integrins
1Department of Surgery, University of Virginia Health System, Charlottesville, VA.
Abstract:
Tumor cell interactions with the local microenvironment influence a range of cellular activities. A ubiquitous and important ";signal"; for tumor cells is the surrounding protein stroma, the extracellular matrix (ECM). This protein network varies in composition and structure throughout the body and within tissues, having a profound effect on the cells interacting with it. Input from these proteins regulates normal and tumor cell functions including adhesion, motility, proliferation, apoptosis, and differentiation.
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