Related Experiment Video
Updated: Jun 4, 2026

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
Published on: May 26, 2023
10 targeting in myocardial infarction
Abstract:
Targeting pharmaceuticals to the infarcted myocardium has two primary objectives: the diagnostic imaging of the infarcted myocardium and the delivery of therapeutic agents to compromised myocardial areas. Various diagnostic and therapeutic agents (such as radiolabeled compounds, thrombolytic enzymes, proteolytic drugs, and antioxidants) have been proposed for visualization or treatment of the infarcted myocardium. However, none of these reagents has the specificity for targeting the compromised myocardium. Therefore, the availability of a target-specific delivery system should increase the efficacy of diagnosis and therapy. Furthermore, the existence of such a targeted delivery system may pave the way for the use of new pharmaceuticals that by themselves can be harmful to normal tissues.
More Related Videos
Related Concept Videos
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome IV: Interprofessional Care
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Acute Coronary Syndrome III: Diagnostic Studies
