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Updated: Jun 4, 2026
07:38
Fluorescent Labeling of COS-7 Expressing SNAP-tag Fusion Proteins for Live Cell Imaging
Published on: May 17, 2010
Fluorescent and lanthanide labeling for ligand screens, assays, and imaging
Jatinder S Josan1, Channa R De Silva, Byunghee Yoo
1Department of Chemistry, University of Arizona, Tucson, AZ, USA.
Methods in Molecular Biology (Clifton, N.J.)
|February 15, 2011
Abstract:
The use of fluorescent (or luminescent) and metal contrast agents in high-throughput screens, in vitro assays, and molecular imaging procedures has rapidly expanded in recent years. Here we describe the development and utility of high-affinity ligands for cancer theranostics and other in vitro screening -studies. In this context, we also illustrate the syntheses and use of heteromultivalent ligands as targeted imaging agents.
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