A patient with obstructive jaundice due to bleeding in the common bile duct after ultrasound-guided liver biopsy
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Updated: Jun 4, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
Muneki Igarashi1, Yoshihiro Tei, Fumiyuki Akino
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Tokai School of Medicine, Bouseidai, Isehara, Kanagawa 259-1193, Japan. muneki@tokai-u.jp
Insights
A liver biopsy complication led to bleeding in the gallbladder and common bile duct, causing obstructive jaundice. Endoscopic retrograde cholangiopancreatography successfully removed the bile duct hematoma.
Area of Science:
- Gastroenterology
- Hepatology
- Interventional Radiology
Background:
- Chronic hepatitis C management often involves liver biopsy for staging and treatment guidance.
- Ultrasound-guided liver biopsy is a common diagnostic procedure.
- Complications, though rare, can occur following liver biopsy.
Observation:
- A 63-year-old man undergoing interferon therapy for chronic hepatitis C developed acute right upper abdominal pain post-liver biopsy.
- Emergency computed tomography (CT) revealed bleeding into the gallbladder and common bile duct.
- The patient presented with obstructive jaundice attributed to a common bile duct hematoma.
Findings:
- Endoscopic retrograde cholangiopancreatography (ERCP) confirmed a filling defect consistent with a hematoma in the common bile duct.
- Endoscopic sphincterotomy was performed to facilitate hematoma removal.
- Successful extraction of the bile duct hematoma was achieved.
Implications:
- This case highlights a rare but serious complication of ultrasound-guided liver biopsy.
- Prompt diagnosis and intervention using ERCP are crucial for managing post-biopsy biliary complications.
- Effective management can prevent further morbidity associated with obstructive jaundice.
Abstract:
A-63-year-old man was referred to our hospital for interferon therapy to treat chronic hepatitis C. The patient complained of right upper abdominal pain 1 hour after the ultrasound-guided liver biopsy. Bleeding in the gallbladder and the common bile duct were found on emergency CT. Obstructive jaundice due to the common bile duct hematoma was diagnosed, and endoscopic retrograde cholangiopancreatography(ERCP) was performed, and a filling defect thought to be a hematoma was seen in the bile duct on cholangiography. The hematoma in the bile duct was extracted after endoscopic sphincteroyomy.
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