Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phases of Wound Repair01:28

Phases of Wound Repair

Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Healing I: Introduction01:11

Healing I: Introduction

Healing is the physiological process by which the body restores the integrity and function of damaged tissues following injury. It involves a coordinated interplay of cellular proliferation, extracellular matrix remodeling, and growth factor signaling. The extent and nature of the tissue damage determine whether healing occurs by resolution, regeneration, or replacement.ResolutionResolution represents the most complete form of healing, occurring when the injury is minimal and tissue...
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the exudate's...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.

Journal of translational medicine·2024
Same author

Predictors of germline status for hereditary melanoma: 5 years of multi-gene panel testing within the Italian Melanoma Intergroup.

ESMO open·2022
Same author

Germline ATM variants predispose to melanoma: a joint analysis across the GenoMEL and MelaNostrum consortia.

Genetics in medicine : official journal of the American College of Medical Genetics·2021
Same author

Prevalence of the E318K MITF germline mutation in Italian melanoma patients: associations with histological subtypes and family cancer history.

Pigment cell & melanoma research·2012
Same author

Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy.

Familial cancer·2011
Same author

Five novel germline function-impairing mutations of CYLD in Italian patients with multiple cylindromas.

Clinical genetics·2009

Related Experiment Video

Updated: Jun 4, 2026

Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis
06:36

Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis

Published on: August 21, 2020

Moist wound healing: current concepts and applications.

W Bruno1, M D Kerstein

  • 1Medical Student, Hahnemann University School of Medicine, Philadelphia, PA.

Surgical Technology International
|February 15, 2011
PubMed
Summary

Moist wound healing, supported by occlusive dressings, accelerates tissue repair. This approach is now a standard treatment for various wounds, offering clinicians enhanced control over the healing process.

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Dermatology

Background:

  • Moist wound healing research intensified following Winter's 1962 study.
  • Molecular and cellular studies confirm benefits of moist environments for tissue repair.
  • Occlusive dressings are now a primary treatment for many wound types.

Purpose of the Study:

  • To review the benefits of moist wound healing.
  • To discuss occlusive dressings for achieving a moist wound environment.
  • To highlight advancements in wound care management.

Main Methods:

  • Literature review of scientific and clinical research on moist wound healing.
  • Analysis of molecular and cell biology studies.
  • Examination of occlusive dressing technologies.

More Related Videos

Murine Model of Wound Healing
05:39

Murine Model of Wound Healing

Published on: May 28, 2013

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

Related Experiment Videos

Last Updated: Jun 4, 2026

Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis
06:36

Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis

Published on: August 21, 2020

Murine Model of Wound Healing
05:39

Murine Model of Wound Healing

Published on: May 28, 2013

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

Main Results:

  • Moist wound healing significantly enhances the rate and quality of tissue repair.
  • Occlusive dressings effectively create and maintain a moist wound environment.
  • A variety of advanced dressings offer clinicians greater control over wound healing.

Conclusions:

  • Moist wound healing is a scientifically validated and clinically effective strategy.
  • Occlusive dressings are essential tools for promoting optimal wound healing.
  • Continued research and technological advancements improve wound management outcomes.