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Related Concept Videos

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

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In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
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Liver Histology01:27

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The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
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Liver Physiology01:30

Liver Physiology

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The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
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Liver Regeneration01:24

Liver Regeneration

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The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
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Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

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The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
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Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

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Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
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Related Experiment Video

Updated: Jan 21, 2026

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach
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Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

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Laparoscopic surgery of the liver.

N Katkhouda1, S Mills

  • 1Assistant Professor of Surgery, Chief, Division of Outpatients of Minimally Invasive Surgery, Director of Minimally Invasive Surgery Program, Los Angeles, CA.

Surgical Technology International
|February 15, 2011
PubMed
Summary

The liver is a common site for cancer due to its functions and proximity to organs. Some liver tumors are undetectable with current methods due to exponential growth.

Area of Science:

  • Oncology
  • Hepatology
  • Cancer Biology

Background:

  • The liver performs critical metabolic, detoxification, and filtering functions.
  • It is a frequent site for both primary and metastatic cancers.
  • Liver cancer incidence is influenced by organ proximity and extensive vascular/lymphatic drainage.

Purpose of the Study:

  • To highlight the liver's significance in oncology.
  • To explain the mechanisms of hepatic lesion formation.
  • To underscore the challenges in detecting small liver metastases.

Main Methods:

  • Review of oncological and anatomical principles.
  • Analysis of factors contributing to liver metastasis.
  • Discussion of tumor growth dynamics.

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Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery
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Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery
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Main Results:

  • The liver's unique structure can act as a barrier to cancer cells.
  • Cancer cells can overcome this barrier, forming synchronous or metachronous lesions.
  • Tumor size varies significantly, with some lesions undetectable by conventional means.

Conclusions:

  • The liver's role in oncology is multifaceted.
  • Understanding hepatic lesion development is crucial.
  • Advanced detection methods may be needed for small tumors.