Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Lateralization

Lateralization

Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correlation between resumption of employment and overall survival following awake mapping-based surgery for IDH-mutant grade 2 glioma: a consecutive series with 515 patients.

Journal of neurosurgery·2026

Same author

The future of neurosurgical oncology lies in cognitive neurosciences: understanding brain processing is much more valuable than surgical technology.

Frontiers in oncology·2026

Same author

What is the actual role of intraoperative MRI on long-term onco-functional outcome of surgery for low-grade glioma? A systematic review.

Journal of neuro-oncology·2026

Same author

Intractable epilepsy before and/or after awake functional mapping-based surgery for IDH-mutant grade 2 glioma: a consecutive series of 105 patients.

Journal of neurosurgery·2026

Same author

Individualized multiparadigm mapping and standardized tablet-based task administration during awake craniotomy: associations with return to work and survival in diffuse gliomas.

Journal of neurosurgery·2026

Same author

EDNRB-dependent endothelin signaling reduces proliferation and promotes proneural-to-mesenchymal transition in gliomas.

Molecular oncology·2026

Search research articles

Related Experiment Video

Updated: Jun 4, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

Double dissociation between syntactic gender and picture naming processing: a brain stimulation mapping study.

Jose Garbizu Vidorreta¹, Roser Garcia, Sylvie Moritz-Gasser

¹Department of Neurosurgery, Hôpital Gregorio Marañón, Madrid, Spain.

Human Brain Mapping

|February 15, 2011

Summary

This study reveals distinct brain networks for grammatical gender and naming. Electrostimulation mapping in awake patients shows separate neural pathways for processing syntactic gender versus word retrieval.

More Related Videos

In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats

In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats

Published on: March 23, 2022

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

Related Experiment Videos

Last Updated: Jun 4, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats

In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats

Published on: March 23, 2022

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

Area of Science:

Neuroscience
Psycholinguistics
Neurolinguistics

Background:

The neural underpinnings of syntactic gender processing are not well understood.
Previous research has not clearly delineated the brain regions involved in grammatical gender versus object naming.

Purpose of the Study:

To investigate whether the cortico-subcortical structures for syntactic gender processing and naming are common or distinct.
To map the specific brain areas and pathways involved in grammatical gender in French.

Main Methods:

Used electrostimulation mapping in nine awake patients undergoing glioma surgery in the left hemisphere.
Patients performed picture naming and article selection tasks (for grammatical gender) with and without stimulation.
Analyzed effects of both cortical and subcortical stimulation on linguistic tasks.

Main Results:

Cortical stimulation induced syntactic gender disturbances in the inferior frontal gyrus and posterior middle temporal gyrus, but not naming disorders.
Stimulation of naming-related areas did not cause grammatical gender errors.
Subcortical stimulation lateral to the caudate nucleus also selectively impaired gender processing.

Conclusions:

Demonstrated a double dissociation between syntactic gender and naming processing, supporting independent network models.
Identified the left inferior frontal gyrus (pars triangularis) and posterior left middle temporal gyrus as crucial for grammatical gender.
Revealed the role of white matter pathways, likely part of the superior longitudinal fasciculus, in a distributed cortico-subcortical circuit for syntactic gender.