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Blockage of longitudinal flow in Meniere's disease: A human temporal bone study
Shigetaka Shimizu1, Sebahattin Cureoglu, Shigetoshi Yoda
1Department of Otolaryngology, Tokyo Medical University, Japan.
Conclusion:
Blockage of the endolymphatic duct is a significant finding in Meniere's disease. The position of the utriculo-endolymphatic valve (UEV) and blockage of the ductus reuniens in the temporal bones were not found to be directly indicative of Meniere's disease.
Objective:
Comparison of blockage of the longitudinal flow of endolymph between ears affected by Meniere's disease and normal ears.
Methods:
We examined 21 temporal bones from 13 subjects who had Meniere's disease and 21 normal temporal bones from 12 controls.
Results:
The endolymphatic duct was blocked in five (23%) ears affected by Meniere's disease (p = 0.016). The utricular duct was blocked in 16 (76%) ears affected by Meniere's disease and 11 (52%) normal ears (p = 0.112). The saccular duct was blocked in 6 (28%) of ears affected by Meniere's disease and 16 (76%) normal ears (p = 0.001). The ductus reuniens was blocked in 10 (47%) ears affected by Meniere's disease and 10 (47%) normal ears (p = 1.000).
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