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Detection and Isolation of Campylobacter spp. from Raw Meat

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Published on: February 23, 2024

Campylobacter ureolyticus: an emerging gastrointestinal pathogen?

Susan Bullman¹, Daniel Corcoran, James O'Leary

¹Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland.

FEMS Immunology and Medical Microbiology

|February 16, 2011

Summary

Campylobacter ureolyticus was identified in nearly a quarter of Campylobacter-positive diarrheal samples. This finding suggests Campylobacter ureolyticus may be an emerging enteric pathogen in gastroenteritis cases.

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Published on: October 22, 2013

Area of Science:

Microbiology
Infectious Diseases
Molecular Diagnostics

Background:

Diarrhea is a common gastrointestinal illness, often caused by bacterial pathogens.
Campylobacter species are well-established causes of bacterial gastroenteritis worldwide.
Accurate identification of bacterial pathogens is crucial for understanding disease transmission and developing effective treatments.

Purpose of the Study:

To screen a large cohort of fecal samples from patients with diarrhea for the presence of Campylobacter species.
To specifically identify and quantify Campylobacter ureolyticus within the identified Campylobacter-positive samples.
To investigate the potential role of Campylobacter ureolyticus as an emerging enteric pathogen.

Main Methods:

Utilized a multiplex-PCR system (EntericBio®) for the initial screening of 7194 fecal samples.
Employed 16S rRNA gene analysis for precise identification of bacterial species.
Used highly specific primers targeting the HSP60 gene for confirmation of Campylobacter ureolyticus.

Main Results:

A total of 349 samples tested positive for Campylobacter species.
Campylobacter ureolyticus accounted for 23.8% of the 349 Campylobacter-positive samples.
This study represents the first report of Campylobacter ureolyticus in fecal samples from patients with gastroenteritis.

Conclusions:

Campylobacter ureolyticus is present in a significant proportion of patients experiencing diarrhea.
The data suggest Campylobacter ureolyticus may be an emerging enteric pathogen contributing to gastroenteritis.
Further research is warranted to elucidate the pathogenicity and clinical significance of Campylobacter ureolyticus.