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Intratympanic gentamicin in Ménière's disease: our experience
L Pérez Delgado1, J Fraile Rodrigo, P Astier Peña
1Otorhinolaryngology, Miguel Servet University Hospital, Zaragoza, Spain. layipez@hotmail.com
The Journal of Laryngology and Otology
|February 16, 2011
Summary
Intratympanic gentamicin injections effectively controlled vertigo in most Ménière
Area of Science:
- Otolaryngology
- Neurology
Background:
- Ménière's disease is a chronic inner ear disorder.
- Medical treatments often fail for monolateral Ménière's disease.
Purpose of the Study:
- To evaluate intratympanic gentamicin injection for Ménière's disease.
- To assess efficacy in patients resistant to medical therapy.
Main Methods:
- Prospective study of 71 patients with monolateral Ménière's disease.
- Treatment involved intratympanic gentamicin injections.
- Diagnosis and follow-up used American Academy of Otolaryngology-Head and Neck Surgery criteria.
Main Results:
- Complete vertigo control achieved in 65.6% of patients.
- Complete or substantial vertigo control in 84.37%.
- 18.3% experienced significant hearing loss.
Conclusions:
- Intratympanic gentamicin injection is effective for vertigo control.
- It offers a viable alternative to more invasive procedures.
- Suitable for Ménière's disease refractory to medical treatment.
