Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Phases of Wound Repair01:28

Phases of Wound Repair

Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Healing I: Introduction01:11

Healing I: Introduction

Healing is the physiological process by which the body restores the integrity and function of damaged tissues following injury. It involves a coordinated interplay of cellular proliferation, extracellular matrix remodeling, and growth factor signaling. The extent and nature of the tissue damage determine whether healing occurs by resolution, regeneration, or replacement.ResolutionResolution represents the most complete form of healing, occurring when the injury is minimal and tissue...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Barriers to the use of brachytherapy for treatment of cervical cancer and prostate cancer in low- and middle-income countries.

Expert review of anticancer therapy·2026
Same author

Circadian profile of 24-hour ambulatory blood pressure monitoring in healthy young adults.

The National medical journal of India·2026
Same author

Why Integrative Science Remains Indispensable: Revisiting, Reshaping and Restoring the Relevance of Physiology.

Annals of neurosciences·2026
Same author

Core competencies in prostate HDR brachytherapy: An American Brachytherapy Society Endorsed Competency Framework.

Brachytherapy·2026
Same author

Comparison of intralesional 5-fluorouracil versus intralesional triamcinolone acetonide for keloid treatment: A prospective randomised double-blind controlled study.

Bioinformation·2026
Same author

Unseen Wounds: Conceptualizing the Experience of Emotional Pain as a Distinct Neuropsychological Construct.

Cureus·2026
Same journal

The Significance of Elective Specialty Posting in Improving Awareness of Plastic Surgery among Medical Students in India: A Survey.

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India·2026
Same journal

Systematic Review of Stem Cells in Plastic, Reconstructive, and Aesthetic Surgery: Clinical Application in Anti-Aging Medicine.

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India·2026
Same journal

Assessment of the BAPFAS Program: A Structured Educational Intervention to Enhance Burn Prevention and First Aid Knowledge Among Schoolchildren.

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India·2026
Same journal

Validation and Comparative Assessment of Patient Satisfaction and Quality of Life Questionnaires Among Indonesian Nasal Fracture Patients Post-rhinoplasty.

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India·2026
Same journal

Professionalism, Leadership, and Spiritual Awareness: Reflections from Four Decades in Plastic Surgery.

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India·2026
Same journal

Identifying Somatic Lymph Nodes for VLNT Using Technetium-99m Sulfur Colloid.

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India·2026
See all related articles

Related Experiment Video

Updated: Jun 4, 2026

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
07:45

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Published on: November 6, 2018

Post-burn scars and scar contractures.

Arun Goel1, Prabhat Shrivastava

  • 1Departments of Burns, Plastic, Maxillofacial & Microvascular Surgery, Lok Nayak Hospital & Associated Maulana Azad Medical College, New Delhi - 110 002, India.

Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India
|February 16, 2011
PubMed
Summary
This summary is machine-generated.

Burn survivors face significant challenges with scars and contractures impacting quality of life. This article reviews strategies for preventing and managing these common post-burn deformities.

Keywords:
Burnscontracturespost-burn scarsrelease and cover

More Related Videos

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring
05:54

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring

Published on: November 29, 2024

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
02:49

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

Published on: February 23, 2024

Related Experiment Videos

Last Updated: Jun 4, 2026

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
07:45

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Published on: November 6, 2018

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring
05:54

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring

Published on: November 29, 2024

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
02:49

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

Published on: February 23, 2024

Area of Science:

  • Plastic Surgery
  • Reconstructive Surgery
  • Burn Management

Background:

  • Mortality and morbidity from burns have significantly decreased in recent decades.
  • However, functional and aesthetic impairments from post-burn scars and contractures persist, affecting patient reintegration into society.
  • These deformities present complex challenges beyond initial survival.

Purpose of the Study:

  • To provide an overview of post-burn scars and scar contractures.
  • To discuss the prevention and minimization of these conditions.
  • To outline the principles of managing aesthetic and functional considerations.

Main Methods:

  • This article is a review of existing literature and clinical principles.
  • It synthesizes information on scar formation, contracture development, and treatment modalities.
  • Focus is placed on preventative and conservative management strategies.

Main Results:

  • Effective prevention and early management are crucial for minimizing scar and contracture severity.
  • A multi-faceted approach is often required, combining surgical and non-surgical techniques.
  • Patient outcomes are significantly influenced by the aesthetic and functional results of scar management.

Conclusions:

  • While burn survival rates have improved, addressing the long-term consequences of scarring and contractures remains a critical aspect of burn care.
  • Proactive strategies for prevention and minimization are essential for restoring function and improving the quality of life for burn survivors.
  • Comprehensive management principles are key to achieving optimal aesthetic and functional recovery.