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[Chemical constituent from fruit of Aristolochia contorta]
Yuqiong Xu1, Mingying Shang, Yuewei Ge
1School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Objective:
To study the chemical constituents of the fruit of Aristolochia contorta.
Method:
The compounds were isolated by chromatographic techniques and crystalization, the structures were elucidated by spectrum analysis.
Result:
Fifteen compounds were isolated from the dry fruit of A. contorta, which were six aristolochic acids: aristolochic acid I, aristolochic acid III a, aristolochic acid IVa, aristolochic acid II, aristolochic acid III and aristolochic acid VIIa. Three aristolactams: aristololactam I, aristololactam II and aristololactam IIIa. Three phenolic acids syringic acid, vanillic acid and p-coumaric acid. Three other type compounds: pentacosane acid, beta-sitosterol and daucossterol.
Conclusion:
Aristolochic acid III, aristolochic acid VIIa, aristololactam IIIa, and penfacosane acid were isolated from A. contorta for the first time, and compounds 4-13 were isolated from the furit of A. contorta for the first time.
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