Related Experiment Video
Updated: Jun 4, 2026
Modeling Cataract Surgery in Mice
Published on: December 1, 2023
Microcoaxial torsional cataract surgery 1.8 mm versus 2.2 mm: functional and morphological assessment
Leonardo Mastropasqua1, Lisa Toto, Luca Vecchiarino
1Department of Medicine and Science of Ageing Eye Clinic, University of Chieti G d'Annunzio Laboratory of Biostatistics, Chieti, Italy.
Background And Objective:
To compare functional and morphological outcomes of 1.8-mm versus 2.2-mm microincision coaxial cataract surgery (MCCS).
Patients And Methods:
Thirty eyes of 30 patients that underwent MCCS were randomized to two groups: 1.8-mm MCCS (group 1: 15 eyes) and 2.2-mm MCCS (group 2: 15 eyes).
Results:
There were no significant between-group differences in uncorrected visual acuity, best-corrected visual acuity, keratometric astigmatism, and endothelial cell count. One day postoperatively, a greater increase of corneal thickness at the incision site was observed in group 1 compared to group 2 using anterior segment optical coherence tomography with no significant differences in tunnel morphometric features and confocal microscopy showed more tunnel edema in group 1 versus group 2 that resolved in both groups.
Conclusion:
Both 1.8- and 2.2-mm torsional MCCS were safe and efficient with easy surgical maneuvers and excellent functional and morphological results; 1.8-mm MCCS induced slightly greater tunnel edema shortly after surgery that resolved in the medium term.
Insights
Microincision coaxial cataract surgery (MCCS) using 1.8-mm or 2.2-mm incisions showed comparable visual and corneal outcomes. The 1.8-mm MCCS group experienced transient tunnel edema, resolving over time.
Area of Science:
- Ophthalmology
- Microsurgery
- Cataract Surgery
Background:
- Microincision coaxial cataract surgery (MCCS) is a minimally invasive technique.
- Comparing different microincision sizes is crucial for optimizing surgical outcomes.
Purpose of the Study:
- To compare functional and morphological outcomes of 1.8-mm versus 2.2-mm microincision coaxial cataract surgery (MCCS).
Main Methods:
- Thirty eyes of 30 patients were randomized into two groups: 1.8-mm MCCS (15 eyes) and 2.2-mm MCCS (15 eyes).
- Functional outcomes included visual acuity, while morphological outcomes assessed corneal thickness, astigmatism, and endothelial cell count.
Main Results:
- No significant differences were found in visual acuity, keratometric astigmatism, or endothelial cell count between the groups.
- Anterior segment optical coherence tomography revealed greater corneal thickness at the incision site in the 1.8-mm group one day postoperatively.
- Confocal microscopy indicated more tunnel edema in the 1.8-mm group, which resolved in both groups over time.
Conclusions:
- Both 1.8-mm and 2.2-mm MCCS are safe and effective, offering excellent functional and morphological results.
- The 1.8-mm MCCS induced slightly more transient tunnel edema compared to the 2.2-mm MCCS, with resolution in the medium term.