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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
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Related Experiment Video

Updated: Jun 4, 2026

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis
05:44

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis

Published on: October 13, 2023

Pregnancy and multiple sclerosis.

Mari Stuart, Linda Bergstrom

    Journal of Midwifery & Women'S Health
    |February 18, 2011
    PubMed
    Summary

    Women with multiple sclerosis (MS) can generally conceive and have healthy pregnancies. However, discontinuing MS therapies before conception and managing postpartum relapse risk are crucial for maternal and infant well-being.

    Area of Science:

    • Neurology
    • Reproductive Health
    • Immunology

    Background:

    • Multiple sclerosis (MS) commonly affects women of childbearing age.
    • Understanding MS's impact on pregnancy is vital for healthcare providers.
    • Women with MS require comprehensive information on reproductive health and MS management.

    Purpose of the Study:

    • To review the effects of multiple sclerosis on pregnancy.
    • To provide guidance for healthcare providers caring for pregnant women with MS.
    • To inform women with MS about reproductive health considerations.

    Main Methods:

    • Literature review on multiple sclerosis and pregnancy outcomes.
    • Analysis of disease impact on fertility and gestational age.
    • Evaluation of immunomodulatory therapy, contraception, and breastfeeding in MS patients.

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    Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
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    Published on: February 19, 2021

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    Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis
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    Published on: October 13, 2023

    Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
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    Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

    Published on: February 19, 2021

    Main Results:

    • MS generally does not negatively impact fertility or pregnancy, though a slight increase in small-for-gestational-age newborns is noted.
    • MS symptoms overlap with pregnancy symptoms; birth and anesthesia choices are similar to the general population.
    • Immunomodulatory therapies must be stopped before conception; postpartum relapse risk increases for 6 months, but breastfeeding is safe. Hormonal contraception is permissible, with potential protective effects from estrogen.

    Conclusions:

    • Women with MS can navigate pregnancy with informed management strategies.
    • Discontinuation of MS therapies pre-conception and postpartum monitoring are essential.
    • Estrogen may offer protective benefits against MS progression.