Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corticosterone Under Experimental Manipulation of Nutrition and Parasite Burden in a Wild Rodent System.

Journal of experimental zoology. Part A, Ecological and integrative physiology·2026
Same author

Comparative Transcriptomics Reveals an Extracellular Worm Argonaute as an Ancestral Regulator of LTR Retrotransposons.

Genome biology and evolution·2026
Same author

Age-grading and species identification of male mosquito Anopheles gambiae s.l. using mid-infrared spectroscopy and machine learning.

Scientific reports·2026
Same author

Drivers of Viral Diversity and Sharing in Marine Mammals.

Molecular ecology·2026
Same author

Applying Supervised Machine Learning to Effusion Analysis for the Diagnosis of Feline Infectious Peritonitis.

Bioengineering (Basel, Switzerland)·2026
Same author

Stage-dependent trade-offs in thermal performance: fluctuating temperatures reverse larval and adult fitness in Anopheles gambiae and An. coluzzii.

Journal of medical entomology·2026

Related Experiment Video

Updated: Jun 4, 2026

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure
05:34

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Published on: December 13, 2024

Wild immunology.

Amy B Pedersen1, Simon A Babayan

  • 1Centre for Immunity, Infection and Evolution, Institutes of Immunology & Infection Research and Evolutionary Biology, University of Edinburgh, Ashworth Labs, West Mains Road, Edinburgh EH9 3JT, UK. amy.pedersen@ed.ac.uk

Molecular Ecology
|February 18, 2011
PubMed
Summary
This summary is machine-generated.

Wild immunology bridges lab research with real-world health by studying immune responses in natural populations. This approach links host immunity to fitness and population dynamics, benefiting both ecology and immunology.

More Related Videos

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response
08:24

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Published on: January 12, 2017

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
05:08

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

Related Experiment Videos

Last Updated: Jun 4, 2026

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure
05:34

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Published on: December 13, 2024

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response
08:24

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Published on: January 12, 2017

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
05:08

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

Area of Science:

  • Ecology
  • Evolutionary Biology
  • Immunology

Background:

  • Organisms in wild populations face diverse pathogens and require effective immune regulation to maintain health and avoid disease.
  • Current understanding of immune responses primarily stems from controlled laboratory studies, limiting applicability to natural settings.
  • Natural populations exhibit significant genetic and environmental diversity, necessitating ecological immunology approaches.

Purpose of the Study:

  • To establish 'wild immunology' by linking immune phenotypes to host fitness within natural environments.
  • To develop relevant immune response measures applicable to host-parasite interactions and host/parasite fitness.
  • To integrate immunology with ecology and evolutionary biology for a comprehensive understanding of health in natural systems.

Main Methods:

  • Investigating immune responses in nonmodel organisms within their natural habitats.
  • Measuring immune responsiveness in relation to host and parasite fitness indicators.
  • Leveraging new genomic technologies to facilitate interdisciplinary research.

Main Results:

  • Challenges include technical limitations (reagents, genomes) and statistical complexities (individual/population variation).
  • Affordable genomic technologies are enabling collaborative research between immunologists, ecologists, and evolutionary biologists.
  • Wild immunology provides insights into host health mechanisms and the real-world impact of immune factors.

Conclusions:

  • Wild immunology offers a crucial link between laboratory immunology and the health of humans, wildlife, and domestic animals.
  • This field enhances ecological understanding of host health and fitness mechanisms.
  • It provides immunologists with data on the ecological relevance and health impacts of studied immune factors.