Changes in total body potassium, hemoglobin and bromine space after hypokinesia and physical exercise

It has been demonstrated that hypokinesia diminished muscular activity induces changes in several biochemical total body parameters, including those of potassium, hemoglobin and bromine spaces. Therefore the objective of this study was to evaluate the composition of the body in 5 essentially healthy men, aged 19-23 years, after a 60 days exposure to hypokinesia (HK). For the simulation of the hypokinetic effect the men were kept under a rigorous bed rest regime. Throughout the hypokinetic period the men routinely performed a set of physical exercises (PE). Total body potassium, hemoglobin, bromine space and cell mass were measured in the baseline period (BP) and during readaptation period (RP), that is, after the exposure to HK. There were demonstrable reductions in cell and hemoglobin masses. The impaired potassium and hemoglobin content did not affect concentration thereof in blood. It was concluded that the examined biochemical parameters of human organism underwent certain changes following the exposure to diminished muscular activity conditions, while at the same time it was revealed that PE cannot be used to counteract the development of adverse effects of hypokinesia.