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Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

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Related Experiment Video

Updated: Jun 4, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Hilar biliary obstruction: malignant masquerades.

Anne M Covey1, George I Getrajdman

  • 1Department of Radiology, Indiana University, Indianapolis, Indiana.

Seminars in Interventional Radiology
|February 18, 2011
PubMed
Summary

Malignant masquerades can cause benign biliary obstruction, mimicking cancer. This article details three cases, highlighting clinical, imaging, and pathology to aid diagnosis of these rare conditions.

Keywords:
Biliary obstructionClonorchis sinensisautoimmune pancreatitischemotherapy-induced biliary sclerosis

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Area of Science:

  • Hepatology
  • Gastroenterology
  • Radiology

Background:

  • Biliary obstruction at the hepatic hilus frequently arises from malignancy.
  • Differentiating malignant from benign causes is challenging, especially without clear mass lesions on imaging.

Purpose of the Study:

  • To describe three cases of benign biliary obstruction mimicking malignancy.
  • To familiarize readers with the clinical, radiographic, and pathological features of these entities.

Main Methods:

  • Case series review.
  • Analysis of clinical presentation, cross-sectional imaging findings, and pathological examination.

Main Results:

  • Three cases of benign biliary obstruction were identified.
  • These cases presented features that mimicked malignant lesions on initial evaluation.

Conclusions:

  • Benign biliary obstruction can present as a 'malignant masquerade'.
  • Recognition of these uncommon entities is crucial for accurate diagnosis and appropriate management.