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High-throughput Purification of Affinity-tagged Recombinant Proteins
Published on: August 26, 2012
New insights into the role of TFIIB in transcription initiation
Yuming Wang1, Stefan Ge Roberts
1Faculty of Life Sciences; The Michael Smith Building; University of Manchester; Manchester, UK.
Transcription
|February 18, 2011
Abstract:
The general transcription factor TFIIB plays essential, but as yet unclear, roles in transcription initiation by RNA polymerase II. We recently found that phosphorylation of TFIIB is required for productive transcription. We discuss the implications of this work for the functions of TFIIB in promoter escape and gene loop formation.
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