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Updated: Jun 4, 2026

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness
Published on: August 31, 2016
Stable mixed double donor chimerism: Absence of war doesn't necessarily mean peace
Jens Gertow1, Jonas Mattsson J, Michael Uhlin
1Center for Allogeneic Stem Cell Transplantation and Division of Clinical Immunology; Karolinska Institutet; Stockholm, Sweden.
Abstract:
Double cord blood transplantation has successfully been introduced to remedy the obstacle of a limited stem cell dose in a single cord blood graft. After a short initial period, the sustained hematopoiesis is derived almost exclusively from one of the donated units. In a recent publication in Clinical and Experimental Immunology we investigated two rare individuals in which both cord blood units co-existed for more than two years after transplantation.
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