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Obstetric outcome following cervical conization
Sharon Armarnik1, Eyal Sheiner, Benjamin Piura
1Department of Obstetrics and Gynecology, Soroka University Medical Center, 151, 84105 Beer-Sheva, Israel.
Archives of Gynecology and Obstetrics
|February 18, 2011
Summary
Women who underwent conization, a procedure to remove cervical tissue, face a significantly higher risk of preterm delivery before 34 weeks. This association remains even after accounting for other risk factors, necessitating close monitoring during pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Reproductive Health
- Perinatal Medicine
Background:
- Conization is a common procedure for managing cervical abnormalities.
- Previous studies have suggested a potential link between conization and adverse obstetric outcomes.
- The specific risk of preterm delivery following conization requires further investigation.
Purpose of the Study:
- To evaluate obstetric outcomes in women after conization.
- To specifically assess the risk of preterm delivery (PTD) in this patient group.
Main Methods:
- Population-based study comparing pregnancies in women with and without a history of conization.
- Multivariable logistic regression analysis was employed to control for confounding variables.
- Data included over 104,000 deliveries, with 53 women having undergone conization.
Main Results:
- Conization, particularly loop electrosurgical excision procedure (LEEP), was associated with advanced maternal age, PTD before 34 weeks, low birth weight, and cervical incompetence.
- The risk of PTD before 34 weeks was significantly elevated in women post-conization (OR 7.73).
- This increased risk of PTD persisted after adjusting for confounders (OR 2.8).
Conclusions:
- A significant association exists between conization and preterm delivery before 34 weeks.
- This association remains robust even after controlling for potential confounding factors.
- Close surveillance of pregnancies in women post-conization is crucial for early detection and management of preterm labor.
