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Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Nursing Ethical Principles II01:27

Nursing Ethical Principles II

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Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
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What is Cancer?02:12

What is Cancer?

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Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
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Related Experiment Video

Updated: Jun 4, 2026

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
08:55

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

Published on: November 30, 2016

Understanding cachexia in patients with cancer.

Susan Holmes1

  • 1Faculty of Health and Social Care, Canterbury Christ Church University, Kent. susan.holmes@canterbury.ac.uk

Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
|February 19, 2011
PubMed
Summary

Cancer cachexia is a complex metabolic syndrome causing significant weight loss in cancer patients. Understanding this condition is crucial due to its high prevalence and impact on patient mortality and well-being.

Area of Science:

  • Oncology
  • Metabolic Disorders
  • Clinical Nutrition

Background:

  • Cancer cachexia is a prevalent and severe metabolic syndrome in cancer patients.
  • It is characterized by the loss of both adipose tissue and lean body mass.
  • This syndrome significantly impacts patient morbidity, mortality, and overall quality of life.

Purpose of the Study:

  • To highlight the importance of understanding cancer cachexia.
  • To emphasize its complex metabolic nature.
  • To underscore its significant effects on patient health outcomes.

Main Methods:

  • Literature review on cancer cachexia.
  • Analysis of prevalence and impact data.
  • Synthesis of current understanding of the syndrome.

Related Experiment Videos

Last Updated: Jun 4, 2026

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
08:55

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

Published on: November 30, 2016

Main Results:

  • Cancer cachexia is a progressive wasting syndrome.
  • It involves the loss of both fat and muscle mass.
  • The syndrome is a major contributor to cancer-related mortality.

Conclusions:

  • Cancer cachexia requires significant clinical consideration.
  • Its metabolic complexity necessitates further research.
  • Addressing cachexia is vital for improving cancer patient survival and care.