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Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Evolution of Microbial Genome01:08

Evolution of Microbial Genome

Microbial genome evolution is a highly dynamic process shaped by continual gene gain and loss across species and strains. This genomic flexibility allows microorganisms to adapt rapidly to environmental pressures and interactions with other organisms. Central to understanding this diversity is the distinction between the core and pan genomes.The core genome comprises the genes shared by all sampled strains of a species, representing essential functions needed for fundamental cellular processes.
Methods to Assess Microbial Communities01:19

Methods to Assess Microbial Communities

Microbial communities, comprising bacteria, archaea, and eukaryotic microorganisms, inhabit diverse ecosystems and play crucial roles in environmental and biological processes. Their diversity is defined by three main parameters: species richness (the number of distinct species), species abundance (the relative quantity of each species), and species evenness (how uniformly individual species are distributed in various locations). These factors together shape the structure and ecological balance...
Introduction to the Human Microbiota01:22

Introduction to the Human Microbiota

Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity, and disease...
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...

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Related Experiment Video

Updated: Jun 4, 2026

Metagenomic Analysis of Silage
08:43

Metagenomic Analysis of Silage

Published on: January 13, 2017

Microbial metagenomics: beyond the genome.

Jack A Gilbert1, Christopher L Dupont

  • 1Plymouth Marine Laboratory, Plymouth PL1 3DH, United Kingdom. gilbertjack@gmail.com

Annual Review of Marine Science
|February 19, 2011
PubMed
Summary

Metagenomics has revolutionized marine microbial ecology, revealing vast genomic data from seawater. Continued exploration promises deeper insights into ocean life and microbial ecosystems.

Area of Science:

  • Marine Biology
  • Genomics
  • Microbial Ecology

Background:

  • Marine microbial metagenomic databases contain billions of DNA base pairs, yet represent a small fraction of available genetic material in seawater.
  • The advent of next-generation sequencing technologies has transformed individual laboratory capabilities.
  • The Global Ocean Sampling expedition has been instrumental in generating large-scale metagenomic data.

Purpose of the Study:

  • To review the impact of metagenomics on understanding marine microbial communities.
  • To discuss recent studies and discoveries in marine metagenomics since 2008.
  • To predict the future of metagenomics in marine microbial ecology.

Main Methods:

  • Analysis of data from the Global Ocean Sampling expedition.

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Microbial Communities in Nature and Laboratory - Interview
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Microbial Communities in Nature and Laboratory - Interview

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Last Updated: Jun 4, 2026

Metagenomic Analysis of Silage
08:43

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Published on: January 13, 2017

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
11:23

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

Published on: December 22, 2014

Microbial Communities in Nature and Laboratory - Interview
29:13

Microbial Communities in Nature and Laboratory - Interview

Published on: May 28, 2007

  • Review of next-generation sequencing applications in marine metagenomics.
  • Discussion of bioinformatic analyses, including conceptual pipelines and sequence annotation.
  • Main Results:

    • Metagenomics has significantly expanded our knowledge of marine microbial diversity and function.
    • Recent studies have yielded novel discoveries in marine microbial ecosystems.
    • Bioinformatic tools are crucial for interpreting complex metagenomic datasets.

    Conclusions:

    • Metagenomics offers unprecedented views into marine microbial communities.
    • Future collaborative studies are essential to address fundamental questions in marine microbial ecology.
    • The field is rapidly advancing, with trillion-base-pair sequencing becoming feasible.