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Published on: October 25, 2015
[Chronic Q fever during pregnancy].
Janna M Munster1, Carl J C M Hamilton, Alexander C A P Leenders
1Universitair Medisch Centrum Groningen, afd. Obstetrie en Gynaecologie, Groningen, the Netherlands. j.munster@og.umcg.nl
A pregnant woman developed chronic Q fever. Treatment options were limited due to pregnancy and allergies, necessitating empirical erythromycin. Intensified monitoring is advised for pregnant women with Q fever.
Area of Science:
- Infectious Diseases
- Obstetrics & Gynecology
- Public Health
Background:
- Q fever, caused by Coxiella burnetii, can present with pneumonia and has a risk of chronicity, particularly in pregnant individuals.
- Standard treatments like doxycycline and hydroxychloroquine are contraindicated during pregnancy.
- Patient presented with pneumonia, later diagnosed as acute Q fever, followed by an unexpected pregnancy.
Observation:
- The patient developed chronic Q fever infection during pregnancy.
- Allergic reactions to co-trimoxazole and contraindications for other antibiotics limited treatment options.
- Erythromycin was administered empirically during pregnancy.
Findings:
- Despite treatment challenges, the patient carried the pregnancy to term.
- Labor was induced at 38 weeks and 2 days due to maternal indication.
- A healthy male infant was delivered via Cesarean section.
Implications:
- This case highlights the diagnostic and therapeutic challenges of Q fever in pregnancy.
- Intensified serological monitoring is recommended for pregnant patients with a history of acute Q fever.
- Early detection and management are crucial to mitigate risks to both mother and fetus.
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