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Updated: Jun 4, 2026

Analysis of the Epithelial Damage Produced by Entamoeba histolytica Infection
Published on: June 12, 2014
A Sequential Model of Host Cell Killing and Phagocytosis by Entamoeba histolytica
Adam Sateriale1, Christopher D Huston
1Department of Medicine, College of Medicine, The University of Vermont, Room 320 Stafford Hall, 95 Carrigan Drive, Burlington, VT 05405, USA.
Abstract:
The protozoan parasite Entamoeba histolytica is responsible for invasive intestinal and extraintestinal amebiasis. The virulence of Entamoeba histolytica is strongly correlated with the parasite's capacity to effectively kill and phagocytose host cells. The process by which host cells are killed and phagocytosed follows a sequential model of adherence, cell killing, initiation of phagocytosis, and engulfment. This paper presents recent advances in the cytolytic and phagocytic processes of Entamoeba histolytica in context of the sequential model.
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