Central receptor sites for angiotensin-induced drinking: a critical review

A review of proposed sites of the dipsogenic action of angiotensin II is presented. Techniques used for such localization are critically discussed, and it is suggested that convergence of evidence from several different experimental techniques is required for localization of dipsogenic receptors. Loci suggested as such sites of action include the preoptic regions, the subfornical organ, and the tissue proximal to the optic recess of the third ventricle, including the organum vasculosum laminae terminalis. Current evidence suggests that there are at least two loci within the forebrain that possess dipsogenic receptors for angiotensin II.