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Updated: Jun 4, 2026

A Workflow to Quantitatively Determine Age-Related Macular Degeneration Lesion-Specific Variations in Fundus Autofluorescence
Published on: May 26, 2023
Utility values in Japanese patients with exudative age-related macular degeneration
Yasuo Yanagi1, Takashi Ueta, Ryo Obata
1Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan. yanagi-tky@umin.ac.jp
Purpose:
To investigate the utility values associated with visual loss due to age-related macular degeneration (AMD) in Japanese patients.
Methods:
Utility values in 48 Japanese patients with bilateral exudative AMD were measured using the time trade-off and standard gamble methods.
Results:
The time trade-off method utility values correlated with the best-corrected visual acuity (BCVA) in the better-seeing eye. The estimated utility values according to the BCVA in the better-seeing eye were 0.534 (BCVA, 0.01-0.15), 0.574 (0.2-0.3), 0.613 (0.4-0.6), and 0.653 (0.7-1.0). The utility values obtained by the standard gamble method were not significantly correlated with BCVA in the better-seeing eye.
Conclusions:
The present results concur with those of previous studies showing that AMD causes a substantial decrease in patient utility values. The utility values obtained in the current study provide important information for use in cost-utility analysis of interventions for Japanese AMD patients.
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