Related Experiment Video
Updated: Jun 4, 2026
12:52
Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
A disulfide-linked naphthalimide dimer for Hg(II) detection in aqueous solution
Yamin Li1, Xiaoling Zhang, Baocun Zhu
1Key Laboratory of Cluster Science of Ministry of Education, Department of chemistry, School of Science, Beijing Institute of Technology, Beijing 100081, People's Republic of China.
Journal of Fluorescence
|February 19, 2011
Summary
A novel disulfide-linked naphthalimide dimer probe detects mercury ions (Hg2+) with high selectivity and sensitivity. This reversible probe offers a turn-on fluorescence response, crucial for environmental and biomedical mercury detection.
Area of Science:
- Chemical Sensors
- Analytical Chemistry
- Materials Science
Background:
- Mercury ions (Hg2+) pose significant environmental and health risks.
- Sensitive and selective detection methods for Hg2+ are crucial for monitoring and safety.
Purpose of the Study:
- To design and synthesize a novel disulfide-linked naphthalimide dimer probe for mercury ion recognition.
- To evaluate the probe's selectivity, sensitivity, and response mechanism towards Hg2+.
Main Methods:
- Synthesis of a disulfide-linked naphthalimide dimer.
- Spectroscopic analysis (fluorescence) for metal ion detection.
- Testing selectivity against various metal ions.
- Determining the detection limit and linear response range for Hg2+.
Main Results:
- The probe demonstrated high selectivity and sensitivity for Hg2+ over other metal ions.
- A turn-on and reversible fluorescence response to Hg2+ was observed in neutral buffer.
- A linear response for Hg2+ was achieved from 0 to 150 μM with a detection limit of 0.38 μM.
- Fluorescence enhancement reached approximately 7-fold upon addition of 150 μM Hg2+.
Conclusions:
- The developed probe meets selectivity requirements for biomedical and environmental applications.
- The probe's sensitivity is sufficient for detecting Hg2+ in environmental and biological samples.
- The probe's reversible and turn-on fluorescence response makes it a promising tool for Hg2+ monitoring.
