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Related Experiment Video

Updated: Jun 4, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Intravaginal misoprostol versus Foley catheter for labour induction: a meta-analysis.

N S Fox¹, D H Saltzman, A S Roman

¹Maternal Fetal Medicine Associates, PLLC, New York, USA. nfox@mfmnyc.com

BJOG : an International Journal of Obstetrics and Gynaecology

|February 22, 2011

Summary

Intravaginal misoprostol and transcervical Foley catheter are similarly effective for labor induction. However, Foley catheters are linked to less uterine tachysystole, a key safety consideration.

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Last Updated: Jun 4, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Area of Science:

Obstetrics and Gynecology
Reproductive Medicine
Clinical Trials

Background:

Cervical ripening is crucial for labor induction.
Intravaginal misoprostol and transcervical Foley catheters are common methods.
Evidence comparing these agents requires synthesis.

Purpose of the Study:

To compare the effectiveness and safety of misoprostol versus Foley catheter for labor induction.
To conduct a meta-analysis of randomized trials.

Main Methods:

Systematic literature search of major databases (PubMed, Embase, Cochrane).
Inclusion of prospective randomized trials comparing the two agents.
Meta-analysis using random-effects models to assess primary outcomes.

Main Results:

Nine studies with 1603 patients were analyzed.
No significant differences in time to delivery, cesarean rates, or chorioamnionitis.
Misoprostol use was associated with significantly higher rates of uterine tachysystole.

Conclusions:

Both agents demonstrate comparable efficacy for labor induction.
Transcervical Foley catheter is associated with a reduced incidence of tachysystole.
Choice of agent may depend on balancing efficacy with tachysystole risk.