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Uncontrolled asthma at age 8: the importance of parental perception towards medication

Ellen S Koster1, Alet H Wijga, Gerard H Koppelman

  • 1Division of Pharmacoepidemiology & Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
|February 22, 2011
PubMed

Insights

Uncontrolled asthma in 8-year-olds is linked to lower maternal education and parental beliefs about medication necessity and side effects. Environmental factors and adherence were not associated with asthma control in this cohort.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology
  • Public Health

Background:

  • Asthma remains uncontrolled in a significant number of children despite available treatments.
  • Identifying factors contributing to uncontrolled asthma is crucial for improving patient outcomes.
  • The PIAMA birth cohort study provides a valuable dataset for investigating pediatric asthma determinants.

Purpose of the Study:

  • To identify determinants of uncontrolled asthma at age 8 in children within the PIAMA birth cohort.
  • To explore associations between child/parental characteristics, environmental factors, therapy adherence, and parental medication beliefs with asthma control.

Main Methods:

  • Included 170 children aged 8 using inhaled corticosteroids.
  • Defined uncontrolled asthma based on symptoms, activity limitations, rescue medication use, lung function (FEV1), and unscheduled physician visits.
  • Utilized binomial regression to analyze five groups of potential determinants, including the Beliefs about Medicines Questionnaire.

Main Results:

  • 45% of children (77 out of 170) had uncontrolled asthma.
  • Low maternal education was associated with uncontrolled asthma (RR 1.6).
  • Parental beliefs regarding medication necessity (RR 1.6) and concerns about side effects (RR 1.6) were also linked to uncontrolled asthma.

Conclusions:

  • Environmental factors and therapy adherence were not significantly associated with asthma control in this cohort.
  • Low maternal education and specific parental beliefs about medication are key determinants of uncontrolled childhood asthma.
  • Findings highlight the importance of socioeconomic factors and parental perceptions in managing pediatric asthma.
Abstract

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