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Updated: Jun 4, 2026

Application of Microwave Ablation in Laparoscopic Partial Splenectomy
Published on: November 15, 2024
Laparoscopic resection of an undifferentiated pleomorphic splenic sarcoma
Asra Hashmi1, Eitan Podgaetz, Melanie L Richards
1Mayo Clinic, Rochester, Minnesota, USA; Dow University of Health Sciences, Karachi, Pakistan.
Background:
Splenic tumors are rare. Malignant fibrous histiocytoma (MFH) of the spleen is one of the least common primary splenic tumors. Review of the literature shows that a laparoscopic resection has never been tried.
Method:
We discuss the case of a 76-year-old man with a 7-cm MFH in the spleen and present a review of splenic sarcomas.
Results:
The patient underwent a successful laparoscopic splenectomy; pathology revealed a rare undifferentiated pleomorphic sarcoma of the spleen. A review of the international literature identified 15 additional cases of primary splenic MFH. Survival was rarely longer than 15 months.
Conclusion:
Malignant fibrous histiocytoma of the spleen is an exceedingly rare tumor with a poor prognosis. In experienced hands, laparoscopic splenectomy is a feasible operative choice for primary splenic sarcoma.
