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Related Experiment Video

Updated: Jun 4, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Published on: March 1, 2015

Chapter 15--chew before you swallow.

¹Faculty of Dentistry, McGill University, Montreal, Quebec, Canada.

Progress in Brain Research

|February 22, 2011

Summary

This summary is machine-generated.

This chapter details research on the neural control of mastication, focusing on the masticatory central pattern generator (CPG). It explores how the CPG functions, its modulation by sensory inputs, and its connection to pain.

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Coordinate Mapping of Hyolaryngeal Mechanics in Swallowing

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Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Published on: March 1, 2015

Coordinate Mapping of Hyolaryngeal Mechanics in Swallowing

Coordinate Mapping of Hyolaryngeal Mechanics in Swallowing

Published on: May 6, 2014

Area of Science:

Neuroscience
Motor Control
Physiology

Background:

James P. Lund's research extensively investigated the neural mechanisms underlying mastication.
Mastication is a complex motor behavior controlled by a dedicated neural network.

Purpose of the Study:

To summarize Lund's lifelong contributions to understanding the masticatory central pattern generator (CPG).
To review research on the CPG's organization, function, and modulation by sensory and cortical inputs.

Main Methods:

Analysis of neural circuitry and cellular properties within the masticatory CPG.
Investigation of reflex modulation and afferent excitability.
Exploration of sensory and cortical influences on CPG activity.

Main Results:

Demonstrated that mastication is centrally patterned.
Elucidated the modulation of reflexes and neuronal excitability within the masticatory system.
Characterized the organization and properties of CPG neuronal subpopulations.

Conclusions:

Lund's work significantly advanced the understanding of the masticatory CPG.
Ongoing research explores the role of muscle afferents and the development of chronic muscle pain.