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Published on: January 29, 2018
Poststroke fractures in a bi-ethnic community
Lynda D Lisabeth1, Lewis B Morgenstern, Jeffrey J Wing
1Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA. llisabet@umich.edu
Summary
Mexican Americans have a lower risk of hip fractures after stroke at younger ages but not older ages. Poststroke fracture prevention should target all elderly individuals, regardless of ethnicity.
Area of Science:
- Neurology
- Geriatrics
- Public Health
Background:
- Mexican Americans face higher risks for stroke and fractures than non-Hispanic whites.
- Limited data exists on poststroke fracture risk within the Mexican American population.
Purpose of the Study:
- To investigate and compare poststroke fracture risk between Mexican Americans and non-Hispanic whites.
- To identify demographic and clinical factors influencing fracture risk poststroke.
Main Methods:
- Utilized data from the Brain Attack Surveillance in Corpus Christi Project (2000-2004).
- Identified 2389 stroke cases and cross-referenced inpatient fracture claims.
- Employed survival analysis and Cox regression to compare fracture risk by ethnicity, adjusting for confounders.
Main Results:
- No significant ethnic differences in overall poststroke fracture or hip fracture survival were observed.
- Factors associated with increased fracture risk included older age, female gender, intracerebral hemorrhage, and stroke severity.
- A significant interaction between ethnicity and age for hip fracture risk was found: Mexican Americans showed protection at younger ages but not older ages.
Conclusions:
- Stroke survivors face a substantial risk of fractures, with a 10% incidence within 5 years.
- Mexican Americans exhibit a protective effect against hip fractures at younger ages, diminishing with advanced age.
- Poststroke fracture prevention strategies should encompass elderly Mexican Americans and non-Hispanic whites alike.
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