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Updated: Jun 4, 2026

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches
Published on: April 20, 2021
Germline determination: don't mind the P granules
Matthew R Marcello1, Andrew Singson
1Department of Molecular Genetics, Microbiology and Immunology, UMDNJ-Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ 08854, USA.
Abstract:
A recently identified novel role for PPTR-1, the regulatory subunit of phosphatase 2A, in P granule segregation challenges the belief that P granules are responsible for determining the germline in Caenorhabditis elegans.
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