Related Experiment Video
Updated: Jun 4, 2026

04:41
Measuring Lactase Enzymatic Activity in the Teaching Lab
Published on: August 6, 2018
Lactose intolerance: an unnecessary risk for low bone density.
1Purdue University, West Lafayette, IN, USA.
Nestle Nutrition Workshop Series. Paediatric Programme
|February 22, 2011
Summary
Lactose intolerance affects millions, leading to milk avoidance and increased osteoporosis risk. Management strategies include dietary adjustments and digestive aids for better bone health.
Area of Science:
- Nutrition Science
- Gastroenterology
- Bone Health
Background:
- Lactose intolerance affects 25-50 million Americans and an unknown global population, leading to milk avoidance.
- Milk avoidance is a significant risk factor for low bone density and increased osteoporosis risk.
- Individuals avoiding milk often have lower calcium intake and poorer bone health.
Purpose of the Study:
- To highlight the prevalence and impact of lactose intolerance on bone health.
- To discuss effective management strategies for lactose intolerance.
- To project the growing challenge of lactose intolerance with expanding dairy markets.
Main Methods:
- Literature review on lactose intolerance prevalence and health impacts.
- Analysis of dietary calcium intake and bone health in milk-avoiding populations.
- Examination of management strategies for lactose intolerance.
Main Results:
- Lactose intolerance necessitates milk avoidance, impacting calcium intake and bone density.
- Effective management includes adapting gut bacteria, consuming low-lactose dairy, and using digestive aids.
- Global dairy market expansion may increase lactose intolerance prevalence.
Conclusions:
- Lactose intolerance poses a significant public health challenge, particularly for bone health.
- Accessible management strategies can mitigate the negative health consequences of lactose intolerance.
- Global education and product innovation are crucial for managing lactose intolerance worldwide.
Related Concept Videos
Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Role of Vitamins in Maintaining Bone Health
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Essential Minerals for Bone Health
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Hormones and Bone Tissue
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Skeleton and Calcium Homeostasis
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
Dysbiosis of the Gut Microbiota
The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibrium—referred to as dysbiosis—can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...