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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...

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Development of urologic de novo malignancies after renal transplantation.

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The effects of mineral metabolism markers on renal transplant outcomes.

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Anemia at 1 year after kidney transplantation has a negative long-term impact on graft and patient outcomes.

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Validation of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation in advanced chronic renal failure.

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Causes of unplanned hemodialysis initiation.

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Related Experiment Video

Updated: Jun 4, 2026

Murine Renal Transplantation Procedure
18:48

Murine Renal Transplantation Procedure

Published on: July 10, 2009

Patients with a failed renal transplant.

R Marcén1, J L Teruel Briones

  • 1Department of Nephrology, Ramón y Cajal Hospital, University of Alcalá de Henares, Madrid, Spain. rmarcen.hrc@salud.madrid.org

Minerva Urologica E Nefrologica = the Italian Journal of Urology and Nephrology
|February 22, 2011
PubMed
Summary

Long-term kidney transplant survival remains poor, with many patients needing dialysis after graft failure. Current guidelines for chronic kidney disease patients are recommended, but optimal dialysis strategies and retransplantation considerations require further study.

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Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
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Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET

Published on: April 28, 2013

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Last Updated: Jun 4, 2026

Murine Renal Transplantation Procedure
18:48

Murine Renal Transplantation Procedure

Published on: July 10, 2009

Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
17:13

Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET

Published on: April 28, 2013

Area of Science:

  • Nephrology
  • Transplantation Medicine
  • Renal Replacement Therapy

Background:

  • Long-term kidney transplant graft survival has stagnated despite advances in immunosuppression and recipient care.
  • A significant number of kidney transplant recipients experience progressive graft dysfunction, necessitating a return to dialysis.
  • There are no specific treatment guidelines for patients with failed kidney grafts before initiating dialysis.

Purpose of the Study:

  • To review current management strategies for kidney transplant recipients with graft failure.
  • To discuss the application of chronic kidney disease guidelines to post-transplant patients.
  • To evaluate the role of dialysis modality and graft nephrectomy in managing failed kidney grafts.

Main Methods:

  • Review of existing clinical practice guidelines for chronic kidney disease.
  • Discussion of evidence regarding hemodialysis versus peritoneal dialysis for failed grafts.
  • Analysis of the impact of systematic graft nephrectomy on patient outcomes.
  • Consideration of retransplantation criteria and outcomes.

Main Results:

  • Kidney Disease Quality Initiative guidelines are recommended for managing non-transplant chronic kidney disease patients, potentially applicable to failed graft recipients.
  • The optimal timing and modality (hemodialysis or peritoneal dialysis) for restarting dialysis after graft failure are not clearly established.
  • Systematic graft nephrectomy may improve inflammatory status but its overall benefit requires further investigation.
  • Retransplantation remains the optimal treatment for failed graft recipients, with recurrent diseases not always being a contraindication.

Conclusions:

  • Management of kidney transplant recipients with graft failure lacks specific guidelines, necessitating adaptation of chronic kidney disease protocols.
  • Further research is needed to determine the best dialysis strategy and the role of graft nephrectomy.
  • Retransplantation offers the best outcome, and eligibility criteria should be carefully considered, even in the presence of recurrent diseases.