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Related Experiment Video

Updated: Jun 4, 2026

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

Published on: December 8, 2014

Post-ATHENA and beyond.

Gerald V Naccarelli¹

¹Heart and Vascular Institute, Penn State University College of Medicine, Hershey, PA, USA. gnaccarelli@hmc.psu.edu

Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing

|February 22, 2011

Summary

This summary is machine-generated.

Dronedarone, an amiodarone analog, reduced cardiovascular hospitalizations in atrial fibrillation patients during the ATHENA trial. Further research is needed to understand its full benefits beyond antiarrhythmic effects.

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A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

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Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses

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Published on: September 28, 2018

Area of Science:

Cardiology
Pharmacology

Background:

Dronedarone is an amiodarone analog developed as a safer alternative.
It is effective in suppressing atrial fibrillation/flutter and controlling ventricular response.

Purpose of the Study:

To review the results of the ATHENA trial on dronedarone efficacy.
To explore potential mechanisms beyond antiarrhythmic properties.

Main Methods:

The ATHENA trial was a placebo-controlled, double-blind, parallel-arm study.
It assessed dronedarone 400 mg twice daily for preventing cardiovascular hospitalization or death in atrial fibrillation patients.

Main Results:

Dronedarone significantly reduced cardiovascular hospitalizations in the ATHENA trial.
Sub-analyses of the trial data were also reviewed.

Conclusions:

The study suggests dronedarone's benefits may extend beyond its antiarrhythmic properties.
Future studies are required to elucidate the mechanisms behind dronedarone's beneficial effects.