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Neutrophil Isolation Protocol
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Published on: July 23, 2008

Neutrophils : collection, separation, and activation

S V Culpitt1

  • 1Department of Thoracic Medicine, National Heart and Lung Institute, Imperial College School of Science, Technology and Medicine, London, UK.

Methods in Molecular Medicine
|February 22, 2011
PubMed

Neutrophils are manufactured in the bone marrow from stem cell precursors (myeloblasts) by a series of cell divisions. In healthy individuals only the mature neutrophils enter peripheral blood. They are the most numerous leukocyte subgroup, constituting half of the circulating white cell population. Healthy blood donors typically yield 1 million neutrophils per mL of venous blood.

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