Lobular panniculitis with small vessel vasculitis associated with ulcerative colitis
Enrico Beccastrini1, Giacomo Emmi, Danilo Squatrito
1Department of Biomedicine, Allergology and Clinical Immunology, University of Florence, Viale GB Morgagni 85, 50134, Florence, Italy. enricobcc@virgilio.it
Modern Rheumatology
|February 22, 2011
Summary
A rare case of lobular panniculitis and small vessel vasculitis associated with ulcerative colitis presented with systemic inflammation. Treatment with cyclophosphamide and prednisolone successfully resolved the disease and inflammatory infiltrates.
Area of Science:
- Dermatology
- Rheumatology
- Gastroenterology
Background:
- Lobular panniculitis is an inflammatory condition affecting subcutaneous fat.
- Small vessel vasculitis involves inflammation of small blood vessels.
- Ulcerative colitis is a chronic inflammatory bowel disease.
Observation:
- A rare case presented with fever, skin lesions, and systemic inflammation.
- The inflammation involved visceral fat, indicating widespread disease.
- The condition was associated with ulcerative colitis.
Findings:
- The patient exhibited lobular panniculitis and small vessel vasculitis.
- Systemic manifestations included visceral fat involvement.
- Successful treatment achieved resolution of inflammatory infiltrates.
Implications:
- This case highlights a rare but severe presentation of panniculitis and vasculitis.
- Effective treatment options exist for this complex condition.
- Understanding the link between inflammatory bowel disease and vasculitis is crucial.
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