Related Experiment Video
Updated: Jun 4, 2026
06:30
Using Phage Display to Develop Ubiquitin Variant Modulators for E3 Ligases
Published on: August 27, 2021
Phage display technology
1Department of Immunology, Imperial College School of Medicine, London, UK.
Methods in Molecular Medicine
|February 22, 2011
Abstract:
The development of monoclonal antibody (mAb) technology (1) has had a significant impact on many fields of research, in particular immunology. However, the method has limitations. The use of recombinant DNA technology and demonstration by Smith 1985 (2) that peptides can be expressed on the surface of filamentous bacteriophages have permitted the development of a powerful new methodology for the generation and isolation of novel antibody-based reagents for both research and clinical application.
