Radiolabeling of monoclonal antibodies

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Determining Binding Affinity (KD) of Radiolabeled Antibodies to Immobilized Antigens
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C S Gooden1

  • 1SmithKline Beecham Pharmaceuticals, Essex, UK.

Methods in Molecular Medicine
|February 22, 2011
PubMed

Radiolabeling of monoclonal antibodies (mAbs) is often one of the principal methods for the in vitro and in vivo assessment of these reagents, whether this is determining the affinity of a new reagent, preparing for preclinical testing, or clinically for diagnostic or therapeutic use.

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