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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
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Accelerated partial breast irradiation.

Peter D Beitsch1, Simona F Shaitelman, Frank A Vicini

  • 1Dallas Breast Center, Dallas, Texas, USA. beitsch@aol.com

Journal of Surgical Oncology
|February 22, 2011
PubMed
Summary
This summary is machine-generated.

Accelerated partial breast irradiation (APBI) offers an alternative to whole breast irradiation (WBI) for select early-stage breast cancer patients. APBI demonstrates excellent local control and cosmetic results when targeting the lumpectomy site.

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Area of Science:

  • Oncology
  • Radiation Oncology
  • Surgical Oncology

Background:

  • Whole breast irradiation (WBI) is the standard treatment following breast conservation surgery for early-stage breast cancer.
  • The role and necessity of WBI in all patients are being re-evaluated.
  • Accelerated partial breast irradiation (APBI) has emerged as a potential alternative, focusing radiation on the tumor bed.

Purpose of the Study:

  • To review the current landscape and evidence supporting Accelerated Partial Breast Irradiation (APBI) as an alternative to Whole Breast Irradiation (WBI).
  • To highlight the various techniques developed for delivering APBI.
  • To assess the efficacy of APBI in terms of local control and cosmetic outcomes.

Main Methods:

  • Review of existing literature and studies on Accelerated Partial Breast Irradiation (APBI).
  • Description of diverse APBI delivery modalities including brachytherapy (multicatheter interstitial, MammoSite balloon catheter, single insertion multicatheter devices), 3D conformal external-beam radiation therapy, and intraoperative techniques.
  • Analysis of reported local control rates and cosmetic results from APBI studies.

Main Results:

  • Multiple APBI delivery techniques have been successfully developed and implemented.
  • Studies indicate that APBI achieves excellent local control rates in early-stage breast cancer patients.
  • Cosmetic outcomes following APBI are generally reported as excellent.

Conclusions:

  • Accelerated Partial Breast Irradiation (APBI) is a viable and effective option for select patients with early-stage breast cancer.
  • APBI provides comparable or improved outcomes to WBI in specific patient populations.
  • The development of various APBI techniques offers tailored treatment approaches with favorable results.