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ESIPT-mediated photocycloadditions of 3-hydroxyquinolinones: development of a fluorescence quenching assay for
Bing Xia1, Baudouin Gerard, Danielle M Solano
1Department of Chemistry, Photonics Center, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States.
Organic Letters
|February 23, 2011
Abstract:
Irradiation of 1,2-dimethyl-3-hydroxyquinolinone (DMQ) leads to excited state intramolecular proton transfer (ESIPT) generating a 3-oxidoquinolinium species which undergoes [3 + 2] photocycloaddition with dipolarophiles. A parallel, fluorescence quenching assay using a microplate format has been developed to evaluate fluorescence quenching of this species with a range of dipolarophiles.

