Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Micelles01:30

Micelles

Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...
Mechanisms of Membrane Domain Formation00:59

Mechanisms of Membrane Domain Formation

Different physical properties of lipids and proteins allow them to localize and form distinct islands or domains in the membrane. Some membrane domains are formed due to protein-protein interactions, whereas others are formed due to the presence of specific lipids such as sphingolipids and sterols—for example, large proteins, such as bacteriorhodopsin, aggregate and create distinct domains.
Another mechanism for membrane domain formation involves membrane proteins interacting with cytoskeletal...
Formation of Lipopolysaccharides01:19

Formation of Lipopolysaccharides

Lipopolysaccharides (LPS) are crucial components of the outer membrane of Gram-negative bacteria, serving both structural and functional roles. It contributes to membrane stability and protects bacteria from host immune responses. LPS is composed of three major regions—lipid A, a core oligosaccharide, and an O antigen. The biosynthesis and assembly of LPS involve a highly coordinated set of enzymatic reactions and transport mechanisms. Additionally, LPS is recognized as an endotoxin, triggering...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Soft matrix promotes ciliogenesis in human retinal pigment epithelial cells.

Scientific reports·2026
Same author

Translational Entropy-Driven Competitive and Additive Effects on DNA Higher-Order Structure via Ion Exchange Between Cations of Different Valencies.

Entropy (Basel, Switzerland)·2026
Same author

Effect of short-term early postoperative gait-training using a lightweight hip-assist device on walking-speed recovery after total knee arthroplasty: a pilot study.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs·2026
Same author

Outcomes of Gastric Cancer Surgery in Nonagenarians Compared With Patients Aged 85-89 Years: a Multi-Institutional Study.

Journal of gastrointestinal cancer·2026
Same author

EuroQol 5-Dimension 5-Level Index Value Changes Associated With Clinically Important Functional Improvement in Individuals With Traumatic Spinal Cord Injury: Insights From Mean Change Analysis.

Archives of physical medicine and rehabilitation·2026
Same author

Two-Photon Responsive Amphiphilic Photoswitches as Molecular Modulators of Lipid Order and Curvature.

Langmuir : the ACS journal of surfaces and colloids·2026

Related Experiment Video

Updated: Jun 4, 2026

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film
08:23

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film

Published on: July 10, 2016

Dissipative structure formation in lipid/lipopolymer monolayers.

Peter C Seitz1, Michael Reif, Kenichi Yoshikawa

  • 1Physical Chemistry of Biosystems, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany.

The Journal of Physical Chemistry. B
|February 23, 2011
PubMed
Summary

Researchers observed stripe formation in surfactant films during Langmuir-Blodgett transfer. Transfer speed and subphase viscosity control stripe patterns, revealing insights into dissipative microstructures and phase separation dynamics.

More Related Videos

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer
10:11

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

Published on: April 19, 2021

Sample Preparation using a Lipid Monolayer Method for Electron Crystallographic Studies
04:22

Sample Preparation using a Lipid Monolayer Method for Electron Crystallographic Studies

Published on: November 20, 2021

Related Experiment Videos

Last Updated: Jun 4, 2026

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film
08:23

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film

Published on: July 10, 2016

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer
10:11

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

Published on: April 19, 2021

Sample Preparation using a Lipid Monolayer Method for Electron Crystallographic Studies
04:22

Sample Preparation using a Lipid Monolayer Method for Electron Crystallographic Studies

Published on: November 20, 2021

Area of Science:

  • Materials Science
  • Surface Chemistry
  • Soft Matter Physics

Background:

  • Monomolecular films of surfactant mixtures exhibit complex behaviors during transfer processes.
  • Understanding pattern formation at the three-phase contact line is crucial for thin film technologies.

Purpose of the Study:

  • To investigate the formation of dissipative microstructures in surfactant mixtures during Langmuir-Blodgett transfer.
  • To elucidate the mechanisms governing stripe formation and phase separation.

Main Methods:

  • Langmuir-Blodgett transfer onto a solid substrate.
  • Imaging ellipsometry to characterize local film thickness.
  • Fluorescence microscopy to analyze membrane composition.
  • Systematic variation of transfer speed and subphase viscosity.

Main Results:

  • Continuous, centimeter-long stripes of phase-separated phospholipids and lipopolymers were generated.
  • Stripe-to-stripe distance was controlled by transfer speed and subphase viscosity, ranging from micrometers to submicrometers.
  • At slow transfer rates, stripe formation follows spinodal decomposition kinetics (Cahn-Hilliard equation).
  • At high transfer rates, shear forces become dominant, influencing stripe formation.

Conclusions:

  • Dissipative microstructures form via distinct mechanisms depending on substrate lifting speed.
  • The study provides a framework for controlling thin film morphology through transfer conditions.
  • Insights into phase separation dynamics in lipidic systems are gained.