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[Bacterial osteomyelitis and arthritis in Icelandic children 1996-2005]

Asgeir Thor Masson1, Thorolfur Gudnason, Gudmyndur K Jonmundsson

  • 1Barnaspitali Hringsins, Lanspitali, Reykajavik.

Laeknabladid
|February 23, 2011
PubMed

Insights

Pediatric osteomyelitis and septic arthritis incidence rose in Iceland, particularly in young children. Staphylococcus aureus was the most common pathogen, but culture-negative cases increased, suggesting a need for better diagnostic methods.

Area of Science:

  • Pediatric infectious diseases
  • Musculoskeletal infections

Background:

  • Osteomyelitis and septic arthritis are significant pediatric infections.
  • Understanding causative pathogens and incidence trends is crucial for effective treatment.

Purpose of the Study:

  • To determine the incidence and causative pathogens of osteomyelitis and septic arthritis in Icelandic children.
  • To analyze presenting symptoms and diagnostic patterns.

Main Methods:

  • Nationwide retrospective review of pediatric cases (<18 years) from 1996-2005.
  • Cases divided into three age groups: 0-5, 6-11, and 12-17 years.
  • Comparison of culture-positive and culture-negative cases.

Main Results:

  • 220 cases identified (161 osteomyelitis, 59 septic arthritis).
  • Overall incidence increased significantly, driven by the youngest age group (osteomyelitis).
  • Staphylococcus aureus was the most frequent pathogen; Kingella kingae was second. Culture-negative cases rose significantly.

Conclusions:

  • Increased incidence of pediatric osteomyelitis, especially culture-negative cases in the youngest children.
  • Staphylococcus aureus and Kingella kingae are key pathogens.
  • Enhanced pathogen detection methods may be beneficial for culture-negative cases.
Abstract

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